Acting on intelligence from the National Crime Agency and the French Customs investigation service DNRED, the Moldovan flagged MV Carib Palm was intercepted in the Eastern Channel on Thursday 10 December.
It had sailed from Colombia and was on its way to Gdansk in Poland.
The interception, led by French Customs and supported by Border Force and the Royal Navy patrol vessel HMS Severn, was coordinated by the UK's Portsmouth-based National Maritime Information Centre (NMIC) and the Maritime Analysis and Operational Centre - Narcotics (MAOC-N) in Lisbon.
HMS Severn, once tasked by the NMIC, sped to the Dover Straits where she then spotted the vessel and tracked its movements before it was intercepted by the French authorities.
The ship was taken to the port of Boulogne-sur-Mer where it was searched by French Customs.
The cocaine seizure is believed to be one of the biggest ever made in France.
In the UK the drugs would have had a wholesale value of around £90 million, but if cut and sold at street level purity the haul could have had a potential value in excess of £350 million.
The twelve crew members, who were Georgian, Turkish and Ukrainian, were arrested and now face prosecution in France.
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